The Growing Fill Finish Manufacturing Industry

The Growing Fill Finish Manufacturing Industry

The Fill-Finish industry has been growing at the same rate as overall biopharma manufacturing.  With almost three decades of experience with aseptic fill filling and lyophilization, Abbvie Contract Manufacturing has a broad range of knowledge and expertise in biopharmaceuticals.

Fill-Finish stays very critical to biopharma manufacture. Its operations are mostly performed by CMOs, which dominate what has become a unique Fill-Finish CMO-based industry. The products validate the ongoing trend seen in bioprocessing of manufacturing being produced at a smaller scale, whether due to less product demand or higher yields.

Abbvie Contract Manufacturing services cover Cell line development, Fermentation biotechnology, now-how and proven quality, regulatory, and operational network to help you achieve your milestones of cGMP manufacturing, Process optimization, Analytical characterization, and Validation. We are your complete and best choice for contract manufacturing of therapeutic proteins, vaccines, and Live Microbial Products.

Contract manufacturing organizations are part of the top authorities in the development and adoption of this and other new Fill-Finish technologies. You can always expect more innovations in this area to result from partnerships between the CMOs and their equipment suppliers.

•Parental Drug Products: As a major pharmaceutical partner, we provide all important elements of delivering high-quality parenteral products for commercial and clinical needs.  AbbVie offers two convenient fill-finish options for parental drug products: prefilled syringe and vials.

•Project Management: Excellent project management is an important and determining factor in the success of any project we embark on. Thus, dedicated project management is our top priority. We offer our customers added value with outstanding technologies that increase significantly in the bioprocess efficiency and so reduce the cost of goods.

•Cost-Effective Biologics Manufacturing: We offer innovative technologies for the efficient and cost-effective production of biologics, also including plasma half-life extension, if desired. Enclosing Fill-Finish equipment with the use of isolator technology, in controlled environments, is a major ongoing trend.

AbbVie will leverage its rough comprehensive development and manufacturing support for your vial and syringe drug product formulations. Fill-finish is itself more mechanical and repetitive than other areas of biopharma manufacture, and innovations tend to be incremental, such as improved equipment performance. 

Our goal is to develop a cost-effective and robust manufacturing process that can be validated and yield maximum quantities of high-quality products while observing all processes and product specifications.

Fill-Finish is not the most active area for biopharma innovations, but it operates at the point of the highest product value. It advances risk reduction, product quality, and efficiency which will certainly bring improvements to this segment. 

At AbbVie, our bioprocess development department focuses mainly on process development, material supply for preclinical trials, strain/analytical development, process transfer, and process characterization. We serve customers from different locations such as Germany, Ireland, Italy, the USA, and Puerto Rico. 

Our fill-finish suite in Ireland can be used for filling your bulk drug substance, and also as a stand-alone service offering. We ensure the processes used at fill finish manufacturing facilities follows with EMA standards and FDA guidelines.